Eck and Dayhoff (1966) (Yes, ok with me to upload elsewhere)

http://pevsnerlab.kennedykrieger.org/Graphics/EckDayhoff.html

Report on the Use of Computers in Biology and Medicine. 1960. Robert Ledley had trained as a dentist, but moved to computers as they were coming along. Margaret Dayhoff worked with him, and they were the 2 authors on the COMPROTEIN paper in 1962.

http://books.google.com/books?id=J5grAAAAYAAJ&pg=PP1&output=html You can download a PDF.

Edit to note: I don't know what the legal status of report covers is.

NucleotideSequences 86 87 https://commons.wikimedia.org/wiki/File:NucleotideSequences_86_87.jpeg

https://commons.wikimedia.org/wiki/File:Wellcome_genome_bookcase.png The first printout of the human genome to be presented as a series of books, displayed in the 'Medicine Now' room at the Wellcome Collection, London.

https://commons.wikimedia.org/wiki/File:NCBI_Entrez_CD_1996.jpg

NCBI Entrez CD 1996

Here’s the GCG manual (it cost $4,000 for an academic license in 1995). It's ok with me for you to upload this to wikimedia commons.

I would say this falls into the unconventional file. But it cracks me up, and if someone used it in a presentation I think it would be fun.

Here is the proof. The rat organismal Venn diagram. @DanGraur pic.twitter.com/NbVhFIybp5

— Lior Pachter (@lpachter) October 28, 2014

And this is the National Biomedical Research Foundation (NBRF) Atlas of Protein and Genomic Sequences (June 30, 1994). It was designed to access data from PIR. Also ok to upload this to Wikimedia commons.

Maybe an off-topic, but here is a vintage Hi-C image from "Spatial organization of the Drosophila nucleus: a three-dimensional cytogenetic study" J Cell Sci Suppl 1984:))

Compare to this one from Cell 2012 ("Three-dimensional folding and functional organization principles of the Drosophila genome")

Mark Boguski has an interesting webpage on the History & Philosophy of Computational and Genome Biology

Introducing the National Center for Biotechnology

Genbank 100: https://commons.wikimedia.org/wiki/File:Genbank100CD.jpg

Voila the link but still doesn't show the pic here:

https://commons.wikimedia.org/wiki/File:GATC.JPG

You can use it if you like

http://www.umass.edu/microbio/rasmol/history.htm

http://www.umass.edu/molvis/francoeur/levinthal/lev-index.html

There are some good images over at the EBI 20th anniversary gallery.

via @atulbutte

Teaching toddlers about oligonucleotide synthesis... with beads! Wish it were this easy in real life! #basf14 pic.twitter.com/hI2uauWX6a

— Atul Butte (@atulbutte) November 1, 2014

https://commons.wikimedia.org/wiki/File:Teaching_toddlers_about_oligonucleotide_synthesis_with_beads.jpg

https://commons.wikimedia.org/wiki/File:Genbank63FloppyDisk.jpg

Multi-sample SNP calling circa 1994 by Casey Bergman

.@eperlste ...and before that, you could publish sequences in your abstract pic.twitter.com/OGcp6AX6Ce

— Casey Bergman (@caseybergman) December 9, 2014

I just came across this paper, and the images were new to me. I love the one of accessing GenBank in 1983. But there is also one of amino acid beads and computer code from 1962.

The Experimenter's Museum: GenBank, Natural History, and the Moral Economies of Biomedicine

Bruno Strasser

http://www.jstor.org/stable/10.1086/658657

"W. Goad in front of a terminal accessing the GenBank c. 1983" http://t.co/GGMOmUzha3 via https://t.co/OzKvf02GUL pic.twitter.com/gHyNUcfFxS

— Pierre Lindenbaum (@yokofakun) December 27, 2014

Check this site to inspire you http://www.dnadarwin.org/

I laughed.

Lizards playing poker. Has kind of a vintage vibe and a bioinformatics vibe.

The BEST journal cover ever @OfficialSMBE http://t.co/eojUOpMZ3W

— James McInerney (@jomcinerney) May 10, 2015

Personally I never trusted these floppy disks, @embl tapes ftw! pic.twitter.com/cyBVphcWMN

— Cédric Lood (@AlterSid) March 21, 2018