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build rna 3d model

Dear all

Kindly help me to build 3d model of mRNA and miRNA. Can any body suggest me any tool or software by which I can able to built the 3d model?

rna-seq

3 answers

I usually hate to answer to a question by another question, but: a 3D model of what and what for?

  • RNA 3D Model of the paired region between mRNA and miRNA (seed region)?
  • RNP 3D Model of the full mRNA-miRNA-Ago complex?

N.B.: did you check the structural data available for this kind of system: e.g. PDB ID 3HK2 and related 3D structures?

Yes I check the pdb data. Basically I need a tool or software by which I can build a 3d model of mRNA and miRNA seed region. I also look over a structure in PDB. i.e. 3F73 in which mRNA-miRNA-Ago complex model was given. I need a best tool by which I can be able to build a 3d model.

Have you tried this?

It's pretty late but you can use these tools:

http://genesilico.pl/

ModeRNA: Comparative modeling

SimRNA: de novo refolding

QRNAs: refinement

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