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Bowtie2 align not working

Hi All,

I've downloaded the latest version of Bowtie2 for Windows (bowtie2-2.2.3-mingw-win64.zip), and added the executables directory to PATH. Whenever I try to run something via Bowtie2 I immediately get errors. If I just type 'bowtie2' I already get

'bowtie2-align-s.exe' has stopped working: ERR): Description of arguments failed! Exiting now

I've also tried commands which work perfectly with an older version of Bowtie2, same problem occurs.

Anyone knows what is going on?

windows bowtie2 align

I get exactly the same. Did you ever figure this out?

1 answer

It's probably because of the chip architecture (my case). That means you are trying to install 64 bit (x86_64) software on 32 bit (i386-i686) machine. The last version that is made for 32 bit machines is Bowtie 2.1

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