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Chip-exo peak-pair distribution heatmap

Hi,

Recently I am working with ChIP-exo data and I seperate out maped Chip-exo reads in two files, forwerd and reverse strand.

I have tried the ngsplot for generating a heatmap of peak-pair distribution of mapped reads, but could not able to get desired output.

Can anyone helpme out to make the peak-pair distribution heatmap from forward and reverse strand mapped reads.

chip-seq

3 answers

you may use MACS for ChIP-exo https://github.com/taoliu/MACS/issues/15

You can also use HOMER to generate the heatmaps. They can tell you the gained, maintained and lost peaks between the conditions.

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