How does homozygous allele sequences appear in Sequencing data?
Hi,
I am new to sequencing and mapping reads in NGS data. I am aware of the definition for Homozygous alleles,but how does they appear in sequence. How do they appear in Read data.
Thank you.
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1 answer
Generally most of the bases covering a position will be the same (whether they mostly match or mismatch the reference depends on whether you're looking at a homozygous WT or homozygous variant position).
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Devon Ryan
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