somatic mutations from WGS of CGI
I understand that somatic mutations occur during the development of cell and are not transferred from one generation to other.
I analyzed a whole genome seq data It showed me that there are 30 variations which are specifically somatics in matched tumor vs normal . Of these, 30 only 1 is in exonic region rest are in either promoter, intron, UTR regions. I could not find out how somatic mutations are identified in non exoinc regions. In such case are non exonic mutations with somatic status may be equally valuable or not.
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What was the approach that you used to identify the somatic mutations? What is your question?