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single RNA integration

Dears, I am new to scRNA integrations. The question is:

  1. Is it possible biologically to integrate scRNA 10X datasets with scRNA SmartSeq2 datasets?
  2. Is it possible biologically to integrate scRNA and snRNA datasets?

Thanks!

snrna 10x smartseq2 scrna

Yes and yes. After all, integration (beyond its technical sophistication) is just aligning cells in reduced dimensional space to cluster/visualoze together despite any unwanted variation other than the actual underlying celltype identity. For a better answer please ask a detailed question.

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