I've been having a tremendous amount of difficulty getting *any utility* out of Anthropic's new Fable model. Not only does it refuse to help with …

We've released **Just-DNA-Lite**, an open-source (AGPL-3.0) tool for annotating personal genomes, a from-scratch rewrite of our earlier Just-DNA-Seq. It takes a GRCh38 VCF/VCF.gz (WGS or …

# polars-bio: Blazing-Fast Genomic Interval Operations on Python DataFrames **Title for Biostars:** polars-bio – fast, scalable genomic interval operations on Polars/Pandas DataFrames (now published in …

https://biodatageeks.org/polars-bio/blog/2026/02/20/interval-operations-benchmark--update-february-2026/

My lab develops high performance methods and tools for computational genomics (`salmon`, `oarfish`, `alevin-fry`, etc.). Previously, I've been a pretty outspoken skeptic on the quality …

Dear all, Kick off 2026 by strengthening your data analysis skills with our three essential online courses designed specifically for biologists and life scientists: [- …

Hi everyone, If you’re currently overwhelmed by the number of **online-only bioinformatics courses** and you’re specifically looking for **in-person, hands-on training**, we’re sharing our **ecSeq …

The **Biostar Herald** publishes user submitted links of bioinformatics relevance. It aims to provide a summary of interesting and relevant information you may have missed. …

I wonder why I didn't come across Lior Pachter's Blog earlier https://liorpachter.wordpress.com/ There was a big war going on with two network biology papers: - …

<p>I have run <a href="http://tophat.cbcb.umd.edu/fusion_index.html">Tophat fusion</a> with paired-end RNA-Seq data, but my run was unsuccessful. The error says <code>running 'long_spanning_reads'</code>. I found a post in …