In CHEMBL database, CDK1 exists as CHEMBL308 for single protein and otherwise as complexes with cyclins B1, B, A, E, and D. Since CDK1 is inactive without binding to a cyclin, how do you suggest I proceed with this data wherein can I combine single protein and complexed data under the assumption that the IC50 values for CDK1 (single protein entry) are based on CDK1-cyclin B complex (most common complex) or are they different from protein complex data? As far as I understand, the CDK1 data for single protein is based on indexing from papers where cyclin isn't mentioned but theoretically wouldn't that be incorrectly indexed? Another thing is that while working with this data should I specifically use a particular assay or can I compare different IC50 values?