This is a test version of Biostars. For the public version, visit https://www.biostars.org.
Generating VCF file from Illumina MEGA array

Hi! I am trying to make a VCF file from .ped and .map files from an illumina MEGA array (two sets, each one having some of the samples I need for my analysis). At first I thought this was straightforward just using PLINK, but looking at the SNP Table, I am realizing that this conversion will be more complicated due to the TOP/BOT and +/- strand designations. I think my SNP Table is already in TOP format, but the SNPs are not all on the same strand as the reference, which I need them to be. How do I navigate this system to make my VCF file?

strand vcf snp illumina microarray

0 answers

No answers yet.

Log in to answer this question.