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Juicer(https://github.com/aidenlab/juicer/wiki ) outputs.hicfiles. Then you can usecooler(https://cooler.readthedocs.io/en/stable/ ).both Juicer and cooler could be applied to generate the .hic or .cool file, but none of them could be use to generate/predict high resolution matrix based on low resolution matrix, like EnHiC, HiCRes, or HiCplus.
However, existing tools can not output .hic or .cool files directly, which could not be use to downstream A/B, TAD analysis.
Therefore, I'm looking for software that can generate high - resolution evidence based on low - resolution files and directly output files in .hic or .cool format.