Hi!

I'm new to methylation analysis. I downloaded the metabric methylation counts from https://tanaylab.weizmann.ac.il/metabric_rrbs/. Looking at the promoter_avg_meth, for example, I see that values are between 0 and 1. Are these beta values? If so, I need to convert them to M-values for the differential methylation. But the min is literally 0 and the max is 1. So do I need to correct these values with a small constant before transforming to M values (like 1e-6)? Has anyone experience with this. Thank you very much