Hi all, I have a question regarding the annotation of 450k methylation arrays. I've performed DMP analysis using limma and DMR using DMRcate. The CpGs are annotated with minfi getAnnotation(IlluminaHumanMethylation450kanno.ilmn12.hg19) and DMRs with annotatr:

  annotations <- build_annotations(genome = 'hg19', annotations = c('hg19_enhancers_fantom', 'hg19_cpgs', 'hg19_basicgenes')).

Now, my question is: I have several DM probes that have ENHANCER—TRUE (predicted enhancer elements), but when I annotate the DMR, which includes these probes, no enhancer coordinates are given. Is there some way to unify this?

Thank you!