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DNA methylation data and P values

I am new to dealing with DNA methylation data. I am unable to understand how to calculate P values .My problem is to distinguish between cancerous and non cancerous samples.

r p-values dna-methylation

Which pipeline of DNA methylation analysis did you follow ?

sorry I don't know about pipeline. What do you mean by pipeline? i am using TCGA datasets

Which bioinformatic tool or packages are you using to perform your analysis ? Did you follow a specific tutorial ?

I am using TCGA datasets and R studio and Python as programming language .

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