Entering edit mode
9 days ago
Estevão
•
0
I am new to the field of bioinformatics and would like to buy a computer for my lab that allows the analysis of several single cell samples, probably from fastq files. What specifications and operating system would be ideal for my case?
For choice of OS: Linux to access the large pool of open source software. One may be able to get away with running WSL2 with Win 11 (if you must have windows).
Hardware choice is going to be more tricky. Get the most amount of RAM you can, especially if you are going to be doing Single cell.
It may also help people if you could put a $ figure (or whichever currency you plan to use) in your post as a guide for your budget.
Thank you. My budget is around 20 thousand dollars.
At the same time? You need a server, not a PC. Google around (and search the site as well with keyword "configuration") but you're going to need a few TB of storage, ideally >= 128 GB of RAM and whatever processor is the best these days. Single cell runs (at least cellranger) are memory and time intensive and the FASTQ files + results can get bulky really quick.
You'll probably get away with using one of the other analysis pipelines, like Alevin-fry with much less than 128GB of RAM. Workstations can pretty much get as beefy as most servers these days, although they arn't any cheaper really.