I have a sequence of amino acids like "MVLLV" and I want to know what mRNA corresponds to that, I'm using biopython for this, but I just know the back_transcribe(), to revert the RNA to DNA, how can I do that for amino acids to mRNA?
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written
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brunofelicianodeomena •
1 answer
Genomax already pointed out some threads, but here's another: Convert amino acid sequences into nucleotide sequences
The short answer is there is rarely if ever a good reason to do this. It's computationally challenging to do anything meaningful with the result too.
To add insult to injury, if you're truly after the mRNA representation, not just the coding/exonic sequences, this would be impossible as there's no way to know how long the poly-A tail and other mRNA features beyond just the sequence would appear.
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Consider How to translate protein sequences to Nucleotide sequences? and the warning from @Mensur there and in this thread From amino acid sequence to DNA sequence using Reverse Translate software.
I've fixed your title - there is no need for all caps.