fold change value

In the context of protein fold change, if the value includes the symbol "-", does it mean that the protein is downregulated, indicating a decrease in expression compared to the control conditions?

proteomics gene-expression

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updated 2.5 years ago by Ram

• written 2.5 years ago by Giovana •

1 answer

Yes - it means the condition on the numerator has less quantity than the condition on the denominator. The fraction (fold-change) is < 1, making logFC < 0.

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written 2.5 years ago by Ram

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