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Can optimal cofactors for arcsinh transformation be calculated in parallel?

Hello,

I am using the estParamFlows function from the flowVS package in R on a dataset consisting of some 50000 rows and 40 markers. In the transformation stage, I am using the estParamFlows function to estimate optimal cofactors. My question is, do the cofactor calculations for each marker depend on other markers? Or could these cofactors be found in parallel somehow to hopefully reduce runtime.

Thanks in advance.

parallel r flowcytometry flowcore flowvs

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