This is a test version of Biostars. For the public version, visit https://www.biostars.org.
Is it possible to detect fusion genes by either stranded or unstranded RNA-seq?

I am interested in detecting fusion genes in RNA-seq data. I'm going to use STAR-Fusion. There are two types of RNA-seq, stranded RNA-seq and unstranded RNA-seq. Is it possible to detect fusions in either of these two types? I would appreciate it if you could enlighten me.

rna-seq star-fusion
• 1,150 views • link
written by Apprentice Apprentice

1 answer

Yes, you can detect fusions in both.

Stranded has the advantage that you can find whether an RNA-seq read originated from the plus or minus strand of the DNA template. This has nothing to do with fusion.

• 0 views • link
written by dsull dsull

Thank you for your quick guidance!

• 0 views • link
written by Apprentice Apprentice

Log in to answer this question.

More posts like this