I am doing differential methylation analysis between Healthy and Glioma samples. I was told to use txt files in minfi I have to convert them to a methylset I got this in my merged data for unheathy Glioma samples.

I tried using the following code

methylation_data <- MethylSet(merged_data)
Error in method(object) : all assays must have the same nrow and ncol

How do I use txt files in minfi? How do I convert these into a methylset?

If anyone has a differential methylation code for doing methylation on txt files using minfi please share it. Or if you have a code to convert these merged txt files like shown in the image above to a methylset or a version that minfi can read and use. Please share. Thank you!