thanks for your response sir @Pierre Lindenbaum
this is my vcf file i don't understand MAXGT and POLY. how to remove MAXGT AND POLY, i am go to gwas study but thia MAXGT AND POLY was my problem . pls any one help me.
##fileformat=VCFv4.1
##fileDate=20130319
##source=GenerateReportDataAndVCFv2.2.2.0
##reference=HumanNCBI37_UCSC
##phasing=none
##INFO=<ID=DP,Number=1,Type=Integer,Description="Total Depth">
##INFO=<ID=TI,Number=.,Type=String,Description="Transcript ID">
##INFO=<ID=GI,Number=.,Type=String,Description="Gene ID">
##INFO=<ID=EXON,Number=0,Type=Flag,Description="Exon Region">
##INFO=<ID=FC,Number=.,Type=String,Description="Functional Consequence">
##FILTER=<ID=q20,Description="Quality below 20">
##FORMAT=<ID=GT,Number=1,Type=String,Description="Genotype">
##FORMAT=<ID=GQ,Number=1,Type=Integer,Description="Genotype Quality">
#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT 12AD50320_MAXGT 12AD50320_POLY
chr16 60054 rs62028702 A C 23 PASS DP=9 GT:GQ 0/1:23 0/1:56
chr16 60087 rs62028703 C G 27 PASS DP=13 GT:GQ 0/1:27 0/1:60
chr16 60095 rs62028704 G T 26 PASS DP=13 GT:GQ 0/1:26 0/1:59
chr16 60120 . G A 11 q20 DP=10 GT:GQ 1/0:11 1/0:43
2 answers
while it works, it's safer to use bcftools view -G in.vcf -o output_file.vcf
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bcftools view -G in.vcf -o output_file.vcf
this command I'm used MAXGT AND POLY column removed but how to going GWAS study without sample column information like genotype(GT) and genotype Quality(GQ)information.
This is output result sir
#CHROM POS ID REF ALT QUAL FILTER INFO
chr16 60054 rs62028702 A C 23 PASS DP=9
chr16 60087 rs62028703 C G 27 PASS DP=13
chr16 60095 rs62028704 G T 26 PASS DP=13
chr16 60120 . G A 11 q20 DP=10
Please solve this sir
Would you now please do what others have asked to fulfill the minimum standards for this question? Use a reasonable title, please upvote and accept answers if helpful. That is the least you can do given you expect others to help you.
Your question is not so descriptive but based on the hint of GWAS i think you might want to remove both columns completly.
SO, if you want to remove whole columns 12AD50320_MAXGT and 12AD50320_POLY
assuming you are using linux terminal then use
cut -f 1-9 input_file.vcf > output_file.vcf
No. From the question, it's obvious the user is not bioinformatics savvy. Don't give them unsafe commands. Use well tested tools like bcftools as Pierre recommends.
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Please choose a more descriptive title and tag
of course you have a problem. Please, change the title.
12AD50320_MAXGT 12AD50320_POLY are the name of the samples, this is was set by your upstream command(s).