This is a test version of Biostars. For the public version, visit https://www.biostars.org.
How to assign ortholog name to K numbers

Hello, I am working on a KEGG analysis and I am wondering if there is a way to get a list of KEGG ortholog IDs (i.e. name that corresponds to the K number). Currently, I have to copy the K number and then search it in the KEGG genes database to get the name of the ortholog which is time consuming. What I would like to do is get all of the IDs for my K numbers and put them into my results file so that I do not have to look up the ortholog ID in the KEGG genes database for each K number.

Has anyone been able to do something similar or have any ideas on how to go about doing this? Any input is appreciated, thanks!

kegg orthology

1 answer

There is this file:

https://www.genome.jp/ftp/db/kofam/ko_list.gz

If you download it and unpack, it has the following information (only the first 5 lines):

knum    threshold       score_type      profile_type    F-measure       nseq    nseq_used       alen    mlen    eff_nseq        re/pos  definition
K00001  360.03  domain  all     0.250716        2403    1950    2124    434     12.37   0.590   alcohol dehydrogenase [EC:1.1.1.1]
K00002  435.40  full    all     0.462905        2410    2304    6139    486     6.92    0.590   alcohol dehydrogenase (NADP+) [EC:1.1.1.2]
K00003  275.10  domain  all     0.949102        6313    5409    3281    726     6.09    0.590   homoserine dehydrogenase [EC:1.1.1.3]
K00004  370.77  domain  all     0.821713        1585    1331    1407    445     5.63    0.590   (R,R)-butanediol dehydrogenase / meso-butanediol dehydrogenase / diacetyl reductase [EC>
K00005  323.30  full    all     0.981299        1455    1057    682     366     2.00    0.590   glycerol dehydrogenase [EC:1.1.1.6]

Log in to answer this question.