Is it valid to use UMI-based analysis pipelines for aptamer-based proteomics
General question about the applicability of UMI-based methods for aptamer-based proteomics. Basically, is it bad practice to treat aptamers like UMIs?
Currently working with aptamer-based proteomic data and am struggling to find sufficient tools. If I were to pull from RNA-seq approaches, would UMI-based approaches be the most reflective? The data I have is already normalized from the company and they won't provide the raw data (red flag), so there are some limitations to how I can model it already.
Cheers
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