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How to identify if a differentially expressed protein is ligand or receptor?

Hi All,

I have a list of differentially expressed proteins and would like to know which one of these are either ligands or receptors. How can I identify this?

Appreciate all your help!

Thanks

proteomics

Hi @Matthias Zepper,

Thanks so much for the quick response! Are there any R packages you can share which can help me answer the question?

If you are familiar with R or at least prefer a solution in R then please state it specifically in the question the next time ;-) The Portal which I recommended can do similar things in a GUI without writing any code and is thus typically preferred by wet lab biologists.

Your one-stop shop for anything related to bioinformatics in R is Bioconductor. Please find all relevant annotation packages in their handy overview on their page and also see their workflows registry, which are usually very handy step-by-step guides that can be customized as needed.

I think, this is the database right? Can we do from BioMart annotation package also in R and then in that we can also choose for the gene description and type by which we can identify the gene?? please correct me, if i am wrong

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