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Any biological reason for correlation between CD115-CD88-CD71, and other correlations between CD** proteins ?

Looking on correlations between some CD** proteins , one can see some patterns, but it is not clear - does it have any biological explanation (for example activity in similar cell types) or it is just some artifact. (The analysis below - on single cell data for CD34+ mobilized hematopoetic progenitors (CITE-seq technology - measures BOTH(!) proteins and RNA - in that question I discuss ONLY proteins).

Question: Can you suggest some biological reasons for correlations below :

CD115-CD88-CD71 more than 0.8 - top correlated.

This correlated group: enter image description here

Or this group enter image description here Or these ANTI-correlated pairs: enter image description here

More analysis can be found here: https://www.kaggle.com/code/alexandervc/mmscel-eda-targets-citeseq-02?scriptVersionId=106444735&cellId=52

scrna-seq cd-genes
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updated by jv jv • written by Alexander • Alexander

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