I do some analysis about whole transcriptome analysis recently.

And the ceRNA network construction is critical part among the whole analysis pipeline.

Between the relationship of lncRNA-miRNA-mRNA, I know how to get the targets prediction about lncRNA-miRNA or miRNA-mRNA.

However, I don't understand how to get the relationship of lncRNA and mRNA through MuTaME scores（and p value） .

So who could give me some advice on this question.

Here is the similar description: Subsequently, shared pairs of miRNA-mRNA and miRNA-lncRNA were used to predict ceRNA scores using MuTaME according to the following formula: ceRNA_score = MRE_for_share_miRNA/MRE_for_lncRNA_miRNA; the related P values were calculated using Benjamini and Hochberg’s approach for controlling the false discovery rate.

And MuTaME originates from the article: Coding-Independent Regulation of the Tumor Suppressor PTEN by Competing Endogenous mRNAs. But I have no idea.

I really hope somebody could tell me sth about it .

Very thankful.