Hi Matthias,
Ronald is right of course, but unfortunatly we had no control on the way the samples where collected. Also when planning the study, this question wasnt part of the plan. Its a follow-on from a study we looked at before,which led us to raise this question.
Thanks for your suggestions, i will take a look at them and see if they are suitable. I agree the time is either an effect or not, and problably treating it as an additional predictor is problable the only resionable way to solve this.
Thanks, Dave