Bulk RNAseq with cell type deconvolution?
Hello! I understand there are multiple tools (i.e. MuSic, Cibersort, etc.) nowadays to perform cell type deconvolution from whole tissue bulk rnaseq data. I wonder if there is any method to extract a specific cell type (i.e. smooth muscle cells) from the deconvolution data so I can perform further secondary analysis (i.e pathway enrichment analysis) on this specific type? Thank you!
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theodore.killian •
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shuaizh117 •
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shuaizh117 •
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To my knowledge, CIBERSORTx is the only bulk deconvolution tool that can impute cell-specific expression profiles: https://cibersortx.stanford.edu/
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