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About Per base sequence content: Should I cut the former abnormal 10 bp?

Here is the Per base sequence content part of my sample's fastqc report. It was marked 'fail'. enter image description here Will it influences my following analysis? Should I cut the first few abnormal bases during trimming?

sequence gc content per base fastqc trimming

1 answer

If this is RNA-seq see these previous answers.

Even if this is not RNAseq then it should still be ok. Libraries that use tagmentation can also produce similar profile.

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