Comparison of sequencers (Illumina / BGI)

Hi,

I am looking for comparison of different sequencing platforms notably Illumina and BGI/MGI.

My question refers to sequencing of small gene panels as well as WES (eventually WGS).

I believe some time ago I had seen a Nature (?) article. However if you have any suggestions for reading or any fora and blogs on this subject, I would be grateful.

Thank you in advance!

sequencing generation bgi illumina next

• 1,448 views • link

updated 4.4 years ago by colindaven

• written 4.4 years ago by spanakorice •

2 answers

https://academic.oup.com/nargab/article/2/2/lqaa034/5836690
https://www.meta.org/papers/comparison-between-mgi-and-illumina-sequencing/33864614
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0230301

• 0 views • link

written 4.4 years ago by GenoMax

This is a very comprehensive google doc with some great comparative info:

https://docs.google.com/spreadsheets/d/1GMMfhyLK0-q8XkIo3YxlWaZA5vVMuhU1kg41g4xLkXc/edit#gid=1569422585

• 0 views • link

written 4.4 years ago by colindaven

More posts like this

DNA sequencing from cord blood stem cells
written 4.1 years ago by dodausp

I believe this is more of a broad question; and I am resorting to here because I found very limited (and not specific) information on …
Indels found on WES but not RNA-seq
written 4.2 years ago by argonvibio •

Hello everyone, For context, I have been working on an evaluation of different variant calling programs (LoFreq, HaplotypeCaller, Strelka2...), comparing their ability to identify SNPs …
Herald: The Biostar Herald for Monday, April 18, 2022
written 4.3 years ago by Biostar

The **Biostar Herald** publishes user submitted links of bioinformatics relevance. It aims to provide a summary of interesting and relevant information you may have missed. …
RNA-Seq data from two sources
written 6.2 years ago by d.anderlion •

Good afternoon, I am a RNA-Seq novice with a few questions, and any advice/help/recommended reading would be greatly appreciated. Due to covid-19, and losing access …
Tutorial: introduce a tool for fast identification of SARS-CoV-2 and other microbes from sequencing…
written 6.4 years ago by chen

These tools and resources have been published in `Briefings in Bioinformatics`: https://academic.oup.com/bib/advance-article/doi/10.1093/bib/bbaa231/5917007 fastv is an ultra-fast tool for identification of SARS-CoV-2 and other microbes from …
Recommendations for Whole Genome Sequencing Workflow
written 6.5 years ago by jrleary

My lab is looking to get into Whole Genome Sequencing, and we of course need a processing and analysis pipeline for the data we generate. …
Implementation of the COSMIC database for somatic variant annotation and filtering pipeline for WES…
written 8.1 years ago by svlachavas

Dear Community, I would like to ask a question concerning the putative implementation of the COSMIC database, in a developed somatic filtering and annotation pipeline, …
Forum: How do you organize sequence data (FASTQs)?
written 8.3 years ago by Daniel E Cook

I'm within a lab that has performed a lot of sequencing. We've sequenced a lot of samples, sequencing many over time, on different platforms (Illumina, …
Bias plot from targeted bisulfite sequencing
written 9.9 years ago by bruce.moran

I have targeted methylation sequencing (Roche Nimblegen kit) from FFPE tissue. I know there are several issues with FFPE, but I am seeing a very …
a question about some "basic numbers" for rna-seq experiments
written 11.1 years ago by CrazyB

From my limited experience with genomic DNA NGS, I could calculate how many "genomic samples" (be it WES (~50Mb), WGS (~3Gb), or targeted sequencing) to …