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Relate longitudinal measurement of quantitative variable with gene expression data

Hello,

For several mice, we measured a certain blood marker each day. After a couple of weeks, the mice were sacrificed and we performed bulk RNA-seq.

Now I would like to see, if the expression of some genes is somehow correlated to changes in the blood marker.

Is this kind of analysis even possible if I only have expression data at the end and not throughout the experiment? And if yes, I can somebody give me a pointer what method or package I should use for it?

Any help is very appreciated.

Cheers!

rna-seq longitudinal

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