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SRA paired downloading issue

When downloading samples from ncbi the samples sequence looks like this

TG2011120320121002130002000

What is the problem

paired sra

1 answer

That is data in color space from a technology called SOLiD. Stay away from it if you can. Current aligners do not support this type of data. See: Transforming And Manipulating Color Space Reads

Thank you !!!

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