I have a microarray dataset with accession number GSE92935. It comprises a total of 6 samples (i.e., 1 CONTROL; 1 Keratoconus (Grade-I); 1 Keratoconus (Grade-II); 1 Keratoconus (Grade-III); 1 Keratoconus (Grade-IV); 1 POOLED CLINICAL GRADE.
Can I do DEGs anaylsis with two groups each one having one sample each like 1 control and 1 pooled ?
And secondly, is it worth doing DEGs analysis between 1 pooled and Grade I-IV as they both are Keratoconus samples ?
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prithvi.mastermind •
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Can I do DEGs anaylsis with two groups each one having one sample each like 1 control and 1 pooled ?
No.
And secondly, is it worth doing DEGs analysis between 1 pooled and Grade I-IV as they both are Keratoconus samples ?
Section 2.12 What to do if you have no replicates of the edger manual covers what to do when you have to replicates.
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