hello!

I downloaded TCGA methylation data using TCGAbiolinks package in R.

query<-GDCquery(project = "TCGA-READ", data.category = "DNA Methylation", legacy = F, platform = "Illumina Human Methylation 450", sample.type=c("Primary Tumor"))

GDCdownload(query)

data<-GDCprepare(query)

data<-SummarizedExperiment::assay(data)

I want to use this data to train and test my machine learning model.

I think it has been already transformed to 0-1 scale value.

should I normalize again this data??