Hi everyone.

Has anyone here used the metaSeq package to carry out a meta-analysis of raw counts data from RNA-seq runs from different studies?

I wasn't really clear on some of the terminology used in the tutorial, specifically, what is meant by 'upper' and 'lower' regulated genes (see page 4). I'm guessing this is up- and down-regulated genes? Haven't had much luck yet contacting the authors.

Also keen to hear people's thoughts on this package vs metaRNAseq.

Thanks.