from genome position to protein position
Hello,
Does anyone know a tool to go from genomic positions to protein and to see whether SNPs are (non)synonymous in bacteria?
Doing it manually in IGV would take too much time...
I have experience with Python, R and bash.
Thanks in advance,
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Convert SNPs into text file that VEP can accept (or VCF) and assuming that mentioned bacterial genomes are sequenced and annotated, VEP will furnish syn, non-syn annotations of input SNPs
Thanks, the problem is that my bacterial genome is not on ensembl - I don't see a way to use VEP with a new genome...
is it annotated?
it is annotated
can you share the link for downloading annotated file?
It is this one H37Rv reference genome of Mtb: https://www.ncbi.nlm.nih.gov/assembly/GCF_000195955.2 For some reason it seems to have disappeared from ensembl....