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integrative multiomic data

I have to integrate cancer patients cohort data - protein, mRNA, Methylation, mutation profile to identify genes associated with survival. What may be the best strategy. I have looked at iNMF, icluster plus etc, that are based on different methods but could not find out what may be the best (suitable to combine) all my data. Any suggestion or please share your expertise

Thanks

analysis multiomics integrative

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