I would like to develop a small scale genomic portal that:

1. Accept requests from the user;
2. Search several tables of data (RDS or csv);
3. Perform computations in R;
4. Output the result in the form of graphs. This web app will be running on a remote web server and it should be robust enough that could manage several user requests without breaking... The cBioPortal website (http://www.cbioportal.org/public-portal/) is doing something very similar to what I need (but mine is in a much smaller scale). I know quite a lot of Python and R, but I have no idea where to start. I was thinking about a shiny app in R. I know a little MySQL and I am willing to give it a go if I need... Just not sure where to start. Any suggestions?