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Hi-C merged files

I have downloaded .hic files from a repisotry, which gives me one merged .hic file of two or more replicates of the same sample. Now, while extracting intra- and interchromosomal interactions I am not really sure how to separate interactions of the replicates. Or do I have only an "avarage" of read counts for each chromosome calculated from both replicates?

hi-c .hic
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written by Oleczkaff • Oleczkaff

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