Screening for high-impact mutations from WES-based variant calling and annotation · Biostar

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Screening for high-impact mutations from WES-based variant calling and annotation

I have performed WES with human sample followed by variant calling by Mutect2 and variant annotations. I am looking at few genes of interest, the problem is that even for those few genes I am getting a lot of variants. Is there any basis of shortlisting variants with probable deleterious impact?? Any suggestions??

variant screening

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updated 5.2 years ago by Pierre Lindenbaum

• written 5.2 years ago by soniabedi.07 •

search this site for VEP, snpEff, annovar....

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written 5.2 years ago by Pierre Lindenbaum

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