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ComplexHeatmap Package takes forever to plot

Hi, I just started self-learning R. I am using the Complex Heatmap package. I have 1 NA cell on every row, but the package says it can process this. My problem is it takes forever to run and I have waited 1 hour after running Heatmap(matrix) multiple times. The dimension of the matrix is 600*21. No plot has come out yet. Has anyone encountered this problem? Any advice would be appreciated.

complexheatmap heatmap
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updated by cpad0112 cpad0112 • written by 5510jingjing1212 • 5510jingjing1212

Can you show us the code that you used andd few lines of the data so that we can reproduce the issue. It is also good practice to paste your sessioninfo.

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written by badribio badribio

Hi Badribio, thank you for helping out. Here's my code: I haven't imputed the NA value in the matrix because I don't see an error. It just takes forever to run. My file is a txt file converted from an Excel sheet.

library("ComplexHeatmap")

filename <- "LibC R1 + -.txt"

lib <- read.table(filename, sep="\t", quote="", na.string = "wt",header=TRUE)

head(lib)

dim(lib)

lib_matrix <- as.matrix(lib[ ,c(2:21)])

lib_matrix

class(lib)

class(lib_matrix)

save column for single amino acid locations for annotation

aminoacid_location <- data.frame(location = lib$X2.5.5)

aminoacid_location

Heatmap(lib_matrix, cluster_columns = FALSE)

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written by 5510jingjing1212 • 5510jingjing1212

Here's the session info:

sessionInfo() R version 4.1.0 (2021-05-18) Platform: x86_64-apple-darwin17.0 (64-bit) Running under: macOS Big Sur 10.16

Matrix products: default LAPACK: /Library/Frameworks/R.framework/Versions/4.1/Resources/lib/libRlapack.dylib

locale: [1] en_US.UTF-8/en_US.UTF-8/en_US.UTF-8/C/en_US.UTF-8/en_US.UTF-8

attached base packages: [1] grid stats graphics grDevices utils datasets methods base

other attached packages: [1] ComplexHeatmap_2.8.0

loaded via a namespace (and not attached): [1] circlize_0.4.12 IRanges_2.26.0 matrixStats_0.58.0 codetools_0.2-18
[5] png_0.1-7 digest_0.6.27 foreach_1.5.1 crayon_1.4.1
[9] stats4_4.1.0 GlobalOptions_0.1.2 doParallel_1.0.16 S4Vectors_0.30.0
[13] GetoptLong_1.0.5 RColorBrewer_1.1-2 rjson_0.2.20 Cairo_1.5-12.2
[17] iterators_1.0.13 tools_4.1.0 parallel_4.1.0 compiler_4.1.0
[21] clue_0.3-59 colorspace_2.0-1 BiocGenerics_0.38.0 cluster_2.1.2
[25] BiocManager_1.30.15 shape_1.4.6

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written by 5510jingjing1212 • 5510jingjing1212

without data, it is difficult to reproduce the issue. Please do not post images of the data.

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written by cpad0112 cpad0112

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