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Herald:The Biostar Herald for Wednesday, June 02, 2021
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11 days ago

The Biostar Herald publishes user submitted links of bioinformatics relevance. It aims to provide a summary of interesting and relevant information you may have missed. You too can submit links here.

This edition of the Herald was brought to you by contribution from Istvan Albert, and was edited by Istvan Albert,

Vcflib and tools for processing the VCF variant call format | bioRxiv (

Dealing with VCF files is a ubiquitous need for bioinformaticians. The VCFlib is project states that

Here we present over 125 useful and much used free and open source software tools and libraries, part of vcflib tools and bio-vcf.

now, unfortunately, this also means that your filesystem will be littered with programs starting the prefix vcf such as:

vcfcreatemulti                vcfmultiway                   vcfsort
vcfdistance                   vcfmultiwayscripts            vcfstats
vcfecho                       vcfnobiallelicsnps            vcfstreamsort
vcfentropy                    vcfnoindels                   vcfuniq

but then we kind of have learned to deal with that, haven't we...

On the bright side if you need to massage VCF files into the right format make sure to check out the project

submitted by: Istvan Albert

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