Bismark Report Merging
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2.9 years ago

I am running Bismark to perform methylation analysis on whole-genome bisulfite sequencing data. To speed up the process I am splitting the paired fastq files into multiple smaller files and aligning them in parallel. I am able to successfully remerge the bam files, dedup, and run the 'bismark_methylation_extractor' tool. I want to use the 'bismark2report' tool, however, it requires a single alignment_report as input. Because of the parallel processing, I have separate alignment reports for each group of split pairs. Is there an existing script that merges these alignment reports into one file that can be read by 'bismark2report --alignment_report <file>?

wbgs methylation bismark • 865 views
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