Hello,
I'm reading the paper "Smyth, G. K. (2004). Linear models and empirical Bayes methods for assessing differential expression in microarray experiments. Statistical Applications in Genetics and Molecular Biology Volume 3, Issue 1, Article 3." and in section 8 "Simulation Results" the author "present a simulation study comparing the moderated t-statistic with four other statistics for ranking genes in terms of evidence for differential expression." and he adds "Data sets were simulated with 15000 genes, 300 or p = 0:02 of which were differentially expressed.". Now, I'm a beginner in the field of biostatistics/bioinformatics/R so I would like to know if somewhere there is the code to reproduce this method of simulation of data sets to compare statistics, as I would like to learn the implementation details.
Thank you very much for your time.
