I am learning how limma package works and diving into the world of bayesian statistics and linear algebra. Feeling frustrated because, I cannot fully explain what the these formula below mean. I am wondering whether my understanding of the name of variable is correct.
๐ฝย ฬ_๐๐=๐_๐^2 ๐ถ^๐ (๐^๐ ๐_๐ ๐)^(โ1) ๐ถ : linear model
(๐ _๐ )ย ฬ^2=(๐_0 ๐ _0^2+๐_๐ ๐ _๐^2) / (๐_0+๐_๐ ) : empirical bayes
๐กย ฬ_๐๐=๐ฝย ฬ_๐๐/(๐ข_๐๐ ๐ ย ฬ_๐ ) : moderated-t
[ ๐ฝย ฬ_๐๐ --> maximum likelihood estimator ] [ ๐_๐^2 --> variance ] [ X --> design matrix ] [ C --> contrast matrix ] [ V --> weight matrix ]
[ (๐ _๐ )ย ฬ^2 --> residual variance ] [ ๐_0, ๐_๐ --> degrees of freedom ] [ ๐ _0, ๐ _๐ --> variance ]
[ ๐กย ฬ_๐๐ --> t value ] [ ๐ข_๐๐ --> standard deviation ]
Are my understanding true ?
I would appreciate it if someone could answer. And very sorry for hard to see the formula.... Please see accurate formula in "http://www.uvm.edu/~rsingle/JournalClub/papers/Smyth-SAGMB-2004_eBayes+microarray.pdf"
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https://stats.stackexchange.com/ would be a more suitable community for this.
Thank you for answering my question. Oh, I didn't know this community! All right, I will go and get information.