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driver genes per sample or per group?

When using driver genes prediction tools such as ONCOCLUST in maftools or dNdScv, should we input the variants of per samples? or per group (same treatment/disease)?

Both tutorials use input that were from multiple subjects. Is driver genes are usually described as per group/population instead of subject/sample?

driver genes

Did you get an answer to your query? I have the same question in mind.

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