Nmr Solvent Most Similar To Saline (H20/Water)
What solvent used to determine protein structure is most similar to saline (H20/water)?
Looking through PDB database, I don't see any NMR structures listed as being solved directly with saline or H20/water.
Thank you!
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Istvan Albert
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GreenDiamond
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As a side comment, this question comes from having a peptide of interest whose structure is only determined by NMR in TFE. However, as peptides are small and flexible, their structure may be different in NMR TFE versus NMR H20/salt (or a similarly more biological medium than TFE). So, I am trying to study how small peptides are affected from NMR TFE versus NMR H20/salt. I was able to collect a survey of peptides from PDB database whose structure is determined by NMR TFE. However, I am unable to find any peptides from PDB database whose structure is determined by NMR H20/salt, and was wondering if there is a similar biological medium that I should look for instead of H20/salt. Thank you...