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Hi I would like to know how to find drug composition, means how to know all the chemicals which are ingredients of any particular drug like paracetamol etc. So please help me out by specifying any database which can help me out with my problem? Thanks
5 answers
Sorry about reviving this, but it is a good question.
If you are looking for active ingredients, it is pretty straight forward to find them with RxNorm (alone or via UMLS).
As far as I know, if you are looking for inactive ingredients, this is more difficult. As different manufacturers have different inactive ingredients, you will likely need to know the NDC (or equivalent) of the product you are wanting to know about. From there, you could use UMLS to look up the FDA label ID (aka SPL Set ID) that corresponds to the NDC (SAB=MTHSPL). You can them obtain the XML for that label (either download the SPL library from the FDA web site, or possibly find a RESTful way to access it). The XML file will have inactive ingredients listed with their Unique Ingredient Identifier codes.
If there is an easier way, please let me know.
JLA
you can contact me for detail, we have the detail Drug database, mark.xu at mims.com
Here are two of the best ones:
Merck Index: https://www.rsc.org/merck-index
Pubchem: https://pubchem.ncbi.nlm.nih.gov
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Do you just want active ingredients or do you want all of the binding and other agents that will vary per manufacturer?