What Problems (If Any) Should I Expect When Combining Identifiers Based On Different Releases Of Dbsnp?
hi, i'm pulling dbsnp ids (rsid) from two different datasets that use different versions of dbsnp (132 versus 137), both of which include SNP chromosome coordinates. i was wondering what dangers lie in mixing rsids from different versions together? thanks
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Brian Tsai •
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The most immediate problems would arise from different genomic builds if that is the case as Sudeep commented see: How to map SNP profile from dbSNP build 131 to 132?
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Have you seen How To Map Snp Profile From Dbsnp Build 131 To 132? post ?
Use LiftOver before "mixing rsids". Web interface: http://genome.ucsc.edu/cgi-bin/hgLiftOver Command line: http://hgdownload.cse.ucsc.edu/admin/exe/linux.x86_64/liftOver
If the versions of dbsnp use the same assembly I'm not quite sure how LiftOver helps.