Hello! I want to use the WholeGenomeMultiChromosome.pl script for six frames translation provided in the publication [https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0082981][1]. The paper mentions that it is available at …

Just read this https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1008281 I believe that is why Bioinformatics/Computational Biology exists Thoughts?

In [this article][1] it is said that sequence alignment algorithms can be unihit or multihit. I did not understand what is the difference between unihit …

I want to progress from "bioinformatics user" to "bioinformatics scientist" (as defined here: from the [former][1] to the [latter][2]), and would appreciate thoughts and advice …

I have been reading the following 2 reviews to get an overview of all pathway analysis tools: 1) https://www.nature.com/articles/nmeth.3963 2) https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1002375 Am I right in …

Hi, Anyone knows a good pipeline to call TFBS peaks using chip-seq data in transposable elements? Most of the traditional pipelines rely on uniquely mapped …

I've been reading this paper. The first part of the algorithm makes perfect sense but I'm not sure how the Dirchlet Process plays a role …

I know that mixed infections contain mixture of a few unrelated strains of the same bacterial species ([source][1]). What are the other examples of this …

There is [a very good paper][1] published in Plos Computational Biology titled "Informatics for RNA Sequencing: A Web Resource for Analysis on the Cloud" ([Supplementary …

We recently published a paper and made available a comprehensive human NGS cancer dataset for tool development, algorithm benchmarking, teaching, pipeline evaluation, etc. This data …